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Fever of unknown origin (FUO) is one of the most difficult diagnostic dilemmas in current medicine. The main causes of FUO in developed countries are non-infectious inflammatory diseases, while infections are predominant in developing countries. Among infections, Mycobacterium Tuberculosis (T is the most frequent cause and it can involve multiple tissues and organs. We report a case of FUO in an immunocompetent patient with fever of unknown origin, finally diagnosed with skeletal TB thanks to a multidisciplinary approach, using FDG-P
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