https://www.selleckchem.com/pr....oducts/gsk3326595-ep
Whereas, the inhibitory effect of BBR on ROS, TXNIP expression, NLRP3 inflammasome activation and pyroptosis could be reversed by H2O2 in AML12 cells. This study demonstrates that BBR's inhibitory effect on NLRP3 inflammasome activation and pyroptosis may be mediated by ROS/TXNIP axis in vitro for the first time. Our findings suggest BBR is a potential candidate for the treatment of NASH. Copyright © 2020 Mai, Xu, Xu, Zhao, Ye, Yu, Wang, Lu, Lin, Yang, Gu, Liu, Zhong and Yang.Caspofungin is the first echinocandin antifungal
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