https://www.selleckchem.com/pr....oducts/alw-ii-41-27.
Anorexia nervosa (AN) is prevalent in adolescent girls and is associated with bone impairment driven by hormonal alterations in nutritional deficiency. To assess the impact of estrogen replacement with and without recombinant human insulin-like growth factor-1 (rhIGF-1) administration on bone outcomes. Double-blind, randomized, placebo-controlled 12-month longitudinal study. Seventy-five adolescent and young adult women with AN age 14 to 22 years. Thirty-three participants completed the study. Transdermal 17-beta estradiol 0.1 mg/d
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