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Through scRNA-seq, differentially expressed genes between control and patient lines were identified. Some of these genes, linked to quantitative structural and functional changes, were cardiac specific, explaining the targeted nature of the disease progression seen in patients. The results of this work demonstrate the utility of combining in vitro tools in exploring heart disease mechanics. The extent to which evidence-based treatments are applied to populations not well represented in early stage breast cancer (EBC) trials remains unkno

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