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https://www.selleckchem.com/
PLCs could express E-Cadherin, Oct-4, β-Catenin, Sox2, CD326, C-kit, GPC3, Nanog. The proliferation curve of PLCs and Hep3B cells were similar, and they all could form tumors in nude mice. Flow-sorted C-kit PLCs, as well as C-kit Hep3B cells could highly express Bmi1, Sox2, Oct4, Notch1, Nanog, C-kit, β-Catenin, Smo, Nestin, ABCG2, ABCB1. And they also could clone and form tumors in vivo. But C-kit PLCs were more sensitive to chemotherapy drugs than C-kit liver cancer cell lines. C-kit PLCs had the characteristics of tumor stem cells and were more sensitive

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