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This paper aims to provide a mechanistic recommendation on the research and control of the THP-resulted rDON in municipal wastewater treatment plants. Published by Elsevier Ltd.BACKGROUND The exposome is defined as encompassing all environmental exposures one undergoes from conception onwards. Challenges of the application of this concept to environmental-health association studies include a possibly high false-positive rate. OBJECTIVES We aimed to reduce the dimension of the exposome using information from DNA methylation as a way to mo
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