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01). LV filling pressure according to the 2016 diastolic guideline was compared with peak PFO velocity in 51 patients. Among patients with high filling pressure according to the guidelines (n = 2, peak PFO velocity ≥ 1.7m/s was present in 60% of patients. In patients with normal filling pressure per the guidelines (n = 31), PFO velocity  1.7m/s was present 84%. Sensitivity and specificity were 75% and 92%, respectively, in patients with sinus rhythm, but were only 50% and 57%, respectively, among patients with atrial fibrillation.

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