https://www.selleckchem.com/pr....oducts/5-cholesten-3
During ventricular fibrillation (VF), targeting the excitable gap (EG) of reentry throughout the myocardium with low-energy surface stimulation shows promise for painless defibrillation. However, the Purkinje network may provide alternative pathways for reentry to evade termination. This study investigates the role of the Purkinje network in painless defibrillation. In a computational human biventricular model featuring a Purkinje network, VF was initiated with 4Hz epicardial pacing. Defibrillation was attempted by st