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Cep57 mutant cells defective in Cep63 binding exhibited improper Cep63 and Cep152 localization and impaired Sas6 recruitment for procentriole system, appearing the importance associated with Cep57-Cep63 relationship. Intriguingly, a Cep63 fused to a microtubule (MT)-binding domain of Cep57 functioned in collaboration with Cep152 to put together around stabilized MTs in vitro Thus, Cep57 plays a key role in architecting the Cep63-Cep152 assembly around centriol
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