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Thereby, the SDF-1-CXCR4/CXCR7-axis had been linked with adenosine signaling. But, the part of this SDF-1 receptors CXCR4 and CXCR7 in acute inflammatory peritonitis and peritonitis-related sepsis still stayed unknown. The presented research provides brand new understanding in the procedure of a selective inhibition of CXCR4 (AMD310 and CXCR7 (CCX771) in 2 types of peritonitis and peritonitis-related sepsis by injection of zymosan and fecal answer. We observed a heightened phrase of SDF-1, CXCR4, a