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© The author(s).Near-infrared (NIR) fluorescence imaging was shown as an effective modality in pinpointing the cyst border and distinguishing the tumor cells from healthier structure throughout the oncological surgery. Developing NIR fluorescent probes with a high cyst to background (T/ sign is vital when it comes to total debulking associated with cyst, that will prolong the survival rate of tumefaction clients. Nevertheless, the nonspecific binding and "al
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