https://www.selleckchem.com/pr....oducts/cid755673.htm
Anecdotal reports and open label case studies in humans indicated that the psychedelic alkaloid ibogaine exerts profound anti-addictive effects. Ample preclinical evidence demonstrated the efficacy of ibogaine, and its main metabolite noribogaine, in substance use disorder rodent models. In contrast to addiction research, depression-relevant effects of ibogaine or noribogaine in rodents have not been previously examined. We have recently reported that the acute ibogaine administration induced a long-term increase of brain-derived neur
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