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During prosthodontic clinical practice, the most commonly reported type of failure is the debonding of teeth to the denture base. Incompatible surface conditions at the tooth/denture base interface result in a lack of bonding. This study aimed to study the influence of different surface modifications of acrylic teeth and thermocycling on shear bond strength to polycarbonate denture base material. Eighty cylinder-shaped samples were fabricated. The tested samples were divided into 4 groups (n = 2. Group A represents the control group, gr