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0; 95% CI 2.5-33.. For OSB, associated risks included consanguinity (aOR 14.0, 95% CI 3.5-55.9), relatives with NTDs (aOR 22.4, 95% CI 4.5-112.9), BMI ≥25 kg/m2 (aOR 2.5, 95% CI 1.6-4.2), insufficient gestational weight gain (aOR 1.9, 95% CI 1.1-3.1), and exposures to hyperthermia (aOR 2.3, 95% CI 1.2-4.3), common cold (aOR 6.8, 95% CI 3.6-12.7), and analgesic/antipyretic drugs (aOR 3.6, 95% CI 1.3-10.. Our high rate probably results from exposures to preventable risks, most related to FA, indicating a need for strengthening existing