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Notably, the response with full diastereoselectivity experienced a syn-selective addition process to give exo-adducts. In addition, this protocol exhibited high efficiency and good practical group tolerance to afford the goal thioethers in moderate to great yields. Based on the results of mechanistic investigations, a plausible device had been recommended.Berberine is a naturally happening isoquinoline alkaloid and has been utilized as a significant functional food additive in China because of its numer