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overed first. IL-12 and TNF-α mRNA expression of the spleen were lower in PC and LGG groups compared with the ceftri group(P0. 01). IL-6 mRNA expression level in the LGG group were lower than the ctrl group(P0. 01). The administration of antibiotics in the early life stage might inhibit weight gain, reduce the diversity of intestinal flora, damage functional bacteria and cause long-term inflammation, even though self-recovery ability exist. Lactobacillus might be helpful to alleviate the damage of antibiotics. But no therapeutic

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