https://www.selleckchem.com/pr....oducts/adaptaquin.ht
When spectra differ between earlier (context) and later (target) sounds, listeners perceive larger spectral changes than are physically present. When context sounds (e.g., a sentence) possess relatively higher frequencies, the target sound (e.g., a vowel sound) is perceived as possessing relatively lower frequencies, and vice versa. These spectral contrast effects (SCEs) are pervasive in auditory perception, but studies traditionally employed contexts with high spectrotemporal variability that made it difficult to understand exactly
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