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05). However, SERT gene expression linearly increased with increasing caffeine dosage (p less then 0.01). The impact of caffeine on ADORA1 gene expression was dose dependent and nonlinear. In conclusion, despite the significant effects of caffeine on birds' growth, no significant negative effects of caffeine were observed on the cardiovascular function of resistant chickens. This work provides valuable information for further study on different dosage of caffeine in an animal model.The onset of the COVID-19 pandemic disrupted many aspec

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