https://www.selleckchem.com/pr....oducts/bms-265246.ht
Irritable bowel syndrome (IBS) is characterised by gastrointestinal (GI) and psychological symptoms (e.g., depression, anxiety, and somatization). Depression and anxiety, but not somatization, have already been associated with altered intestinal barrier function, increased LPS, and dysbiosis. The study aimed to investigate the possible link between somatization and intestinal barrier in IBS with diarrhoea (IBS-D) patients. Forty-seven IBS-D patients were classified as having low somatization (LS = 19) or high somatization (HS = 28) a