Mesothelioma Diagnosis A doctor can diagnose the condition through physical exam, imaging tests and laboratory work. Doctors can also conduct biopsy, which entails removing tissue and examining it under a magnifying lens. A chest X-ray or CT scan is used to guide the needle through the lining of the lung. The procedure can be not invasive and could have the potential of producing false-negative results. Diagnosis Mesothelioma is a rare cancer, which means it takes time to make an official diagnosis. Your doctor will begin by taking a medical