https://www.selleckchem.com/pr....oducts/tak-243-mln24
Background Vinclozolin (VCZ) is a widely used antifungal agent with capability to enter into the human food chain. VCZ metabolizes into seven metabolites M1 to M7. Several studies have shown its effects on reprotoxicity. However, there is limited information available on the interaction of VCZ metabolites with nuclear receptors. In silico studies aimed at identifying interaction of endocrine disruptor with nuclear receptors serve a pre-screening framework in risk assessment.Methods We studied interactive potential of VCZ and its
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