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By using these differentially adapted host-parasite associations for experimental studies, host stress responses were examined in the present study in relation to the degree of mutual adaptations between eel hosts and parasites. Under laboratory conditions, Japanese and European eels were each inoculated with A. crassus and Pomphorhynchus sp., respectively, to investigate their stress responses against differently adapted parasites. The stress response was determined by analyzing plasma levels of cortisol, which is the main corticosteroid
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