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Vitamin D deficiency and low physical activity are related with low HDL-C levels. Maintaining sufficient vitamin D levels and physical activity may help prevent dyslipidemia.In 2015, the newborn screening (NBS) programmes in England and Wales were expanded to include four additional disorders Classical Homocystinuria, Isovaleric Acidemia, Glutaric Aciduria Type 1 and Maple Syrup Urine Disease, bringing the total number of analytes quantified to eight phenylalanine, tyrosine, leucine, methionine, isovalerylcarnitine, glutarylcarnitine, o