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001) or non-atrophic areas (P 0.001). FLIO is able to contribute additional information regarding differences in chronic degenerative retinal diseases. Although it cannot replace conventional autofluorescence imaging, FLIO adds to the knowledge in these diseases and may help with the correct differentiation between them. This may lead to a more in-depth understanding of the pathomechanisms related to atrophy and types of progression. Differences between atrophic retinal diseases highlighted by FLIO may indicate separate pathomecha