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No relation was noted between ED patient complexity, based on their CPT code, and the day of the week (P = 0.41). Individual, nonstatistically significant differences between the day of the week and pediatric ED volumes were identified, however. Conclusions We identified no relation between pediatric ED patient complexity, assessed by CPT code, and the day of the week. Furthermore, a more multifactorial and granular analysis may be necessary to model resource constraints by type and time of day to more effectively manage ED resources. C