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Stratified analysis showed the associations of serum UA with GDM were stronger among pregnant women aged 35 years or older. . - We found higher serum UA at 13-18 gestational weeks was a risk factor for GDM. Our findings provide new evidence for the role of serum UA in the prevention and early intervention of GDM, and highlighted the need for monitoring serum UA at 13-18 gestational weeks. . - We found higher serum UA at 13-18 gestational weeks was a risk factor for GDM. Our findings provide new evidence for the role of serum UA in the preventi
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