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To assess the reliability of CXR and to describe CXR findings and clinical and laboratory characteristics associated with positive and negative CXR. Retrospective two-center study on consecutive patients admitted to the emergency department of two north-western Italian hospitals in March 2020 with clinical suspicion of COVID-19 confirmed by RT-PCR and who underwent CXR within 24h of the swab execution. 260 patients (61% male, 62.8 ± 15.8year) were enrolled. CXRs were rated as positive (CXR+) or negative (CXR-), and features reported in