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The aims of this research were to observe yield extract, phytochemical content, the antidiabetic and anticancer activity of Chinese water chestnut. This research method used an experimental laboratory, and data analysis was carried out descriptively. The stages carried of this research are sample extraction, extract yield, phytochemical analysis (flavonoid and phenolic content), antidiabetic, and anticancer activity. The results showed that the yield of extract using ethanol on Chinese water chestnut was higher than that extracts using n-h

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