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nd survivors, particularly in community-based settings. To investigate the application of machine learning-based ultrasound radiomics in preoperative classification of primary and metastatic liver cancer. Data of 114 consecutive histopathologically confirmed patients with liver cancer from January 2018 to November 2019 were retrospectively analyzed. All patients underwent liver ultrasonography within 1week before hepatectomy or fine-needle biopsy. The liver lesions were manually segmented by two experts using ITK-SNAP software. Seven ca