What Causes Trucking Accidents? Trucks make up a small portion of the vehicles on the road but they can cause serious injury or death. Accidents involving large vehicles can result when drivers are distracted or fail to pay attention to their blind spots. Trucking accidents can also be the result of driver fatigue. Drivers work for long hours without taking breaks in order to meet their limits. Driver Error Driver error is the primary reason for trucking accidents, and it's a serious problem. There are a myriad of factors that can contribute