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Challenges of ADHD in Women and Girls Women and girls often face a wide range of challenges when untreated ADHD symptoms interfere with their daily lives. They may feel unprepared at work, experience difficulties with peer relationships or experience anxiety and depression. They are also more adept at building coping mechanisms that conceal their ADHD symptoms, which makes it harder to be diagnosed and treated. Signs and symptoms The gender gap in ADHD is decreasing as we age