https://www.selleckchem.com/pr....oducts/rhapontigenin
At later stages, injecting left-enriched metabolites into the right cell perturbed the expression of genes known to (a) be required for the formation of the gastrocoel roof plate (foxj1); (b) lead to the asymmetric expression of Nodal (dand5/coco); or (c) result from asymmetrical nodal expression (pitx2). Despite these perturbations in gene expression, we did not observe heterotaxy in heart or gut looping at tadpole stages. These studies indicate that altering metabolite distribution at cleavage stages at the concentrations tested
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