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Insufficient renal urate excretion and/or overproduction of uric acid (UA) are the dominant causes of hyperuricemia. Baicalein (BAL) is widely distributed in dietary plants and has extensive biological activities, including antioxidative, anti-inflammatory and antihypertensive activities. To investigate the anti-hyperuricemic effects of BAL and the underlying mechanisms in vitro and in vivo. We investigated the inhibitory effects of BAL on GLUT9 and URAT1 in vitro through electrophysiological experiments and C-urate uptake assays. To eva
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