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20 (0.09-0.47), 0.35 (0.15-0.81), and 0.57 (0.36-0.9 for hospitalizations, ED visits, and restricted activity. For functional decline, the corresponding odds ratios (95% CI) were 5.68 (3.87-8.33), 1.90 (1.13-3.2, and 1.30 (0.96-1.75). The effect sizes for hospitalizations and ED visits were larger than those for the covariates. Intervening illnesses/injuries are common in the year after major surgery, and those leading to hospitalization and ED visit are strongly associated with adverse functional outcomes, with effect sizes larger th