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HKP was verified to keep up the bioactivity associated with parent medication for ameliorating ischemia-reperfusion injury by lowering brain infarction and improving neurologic purpose. Taken collectively, HKP is a potentially useful aqueous-soluble prodrug with enhanced pharmacokinetic properties which may merit further development as a possible medication applicant. © 2018 Shenyang Pharmaceutical University. Posted by Elsevier B.V.Monocarboxylate transporter 1 (
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