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elder patients and those who simultaneously initiate both treatments showed the steeper decrease in eGFR. To conclude, co-administration of SGLT2i and ARNI in routine care in HFrEF patients produced a slight decrease in eGFR at 6 months of follow-up. This decrease was especially significant in elder patients and those who initiate both drugs simultaneously. This was a retrospective cohort study. The aim of this study was to assess the most commonly used components of enhanced recovery after surgery (ERAS) combinations and their re