https://www.selleckchem.com/pr....oducts/Rapamycin.htm
05). AS protected HILI, decreased the MPO and MDA concentration, and reversed TAOC level (P less then 0.05). AS also downregulated the levels of TNF-α, IL-1β, and IL-6 in the premature rat's blood (P less then 0.01). Moreover, AS markedly attenuated AEC II cell apoptosis and increased Nrf2 and Heme oxygenase 1 (HO-1) expression in the nucleus (P less then 0.05). Conclusion AS showed protective effects on premature rats of HILI in vitro and in vivo. AS can potentially be developed as a novel agent for the treatment of HILI diseases.Obj