https://www.selleckchem.com/pr....oducts/danicamtiv-my
Other frequent molecular alterations included the TERT promoter (50%), CDKN2A (25%), FAT1 (17%), PIK3CA (14%), and NOTCH1 (15%) genes. Transforming growth factor-β pathway alterations (4%) were associated with poor OS (P= 0.01) and DFS (P= 0.02) in univariate and multivariate analyses. High TMB was associated with prolonged OS (P= 0.01 and P= 0.02, in the highest 10% and 20% TMB values, respectively), but not with DFS. Correlation of TMB with OS remained significant in multivariate analysis (P= 0.01 and P= 0.005 in the highes
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