https://csnchem.com/seclusion-....as-well-as-character
These impacts were blocked by sulfasalazine, an inhibitor regarding the xCT transporter, which incorporates cystine (precursor of GSH) and extrudes extracellular glutamate, an agonist associated with inhibitory mGlu2/3 receptor, which lowers the synaptic glutamatergic tone. The inhibitor of mGlu2/3 receptor (LY341495) blocked the NAC-induced inhibition of both relapse ethanol intake and neuroinflammation without affecting the GSSG/GS
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