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REPORT OF SIGNIFICANCE In this research, we created 3D radially and vertically aligned nanofiber scaffolds to transplant bone marrow mesenchymal stem cells (BMSCs). We personalized 3D scaffolds that may totally match the scale, depth, and shape of diabetic wounds. Moreover, both the radially and vertically lined up nanofiber scaffolds could totally recuperate their particular form and keep architectural integrity after repeated loads with compressive stresses. Also, the BMSCs-laden 3D scaffolds ar