https://www.selleckchem.com/pr....oducts/guanidine-thi
Furthermore, miR-585 directly targets and decreases the expression of oncoprotein murine double minute 2 (MDM2). More importantly, the restoration of MDM2 via enforced overexpression markedly rescues miR-585 inhibitory effect on human glioma cell proliferation, thus demonstrating that targeting MDM2 is a critical mechanism by which miR-585 inhibits human glioma cell proliferation. Our study unveils the anti-proliferative role of miR-585 in human glioma cells, and also implicates its potential application in clinical therap
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