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8%. The combination of high-speed grinding of hair and SPME had the advantages of being easy to perform, environment-friendly and high in detection sensitivity. The proposed method offered an alternative analytical approach for the sensitive detection of drugs in hair samples for forensic purposes.Key PointsThe SPME was involved for the determination of drugs in hair with LC-MS.The hair high-speed grinding combined with SPME was firstly developed.Good linearity, sensitivity, recovery and precision were achieved.This work presents an odd
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