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The virulence factor S. suis adhesin P (SadP) recognizes the galabiose Galα1-4Gal-oligosaccharide. Based on its oligosaccharide fine specificity, SadP is split into subtypes PN and PO We show right here that subtype PN is distributed in the systemic strains causing meningitis, whereas type PO can be found in asymptomatic carriage and breathing strains. Both forms of SadP are shown to predominantly bind to pig lung globotriaosylceramide
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