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The neutrophil-to-lymphocyte ratio was lower in TH group (0.20 ± 0.02) compared with the normothermic group (0.32 ± 0.03; p = 0.003). TH influenced the levels of blood gases and blood counts, favoring hypothermia over control. TH significantly improved long-term survival and blunted the inflammatory response in experimental hemorrhagic shock.Glutathione S-transferase placental form-positive (GST-P+) foci are markers of preneoplastic lesions in rat hepatocarcinogenesis. Our previous studies using reporter gene transgenic rats showed tha