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Remarkably, stable chlorinated and brominated intermediates or products were not generated in ClO•- and BrO•-mediated subsequent degradations of caffeine. The assessment of aquatic toxicity and health effects showed that caffeine could penetrate the blood-brain barrier (human), and caffeine and its degradation products were potentially harmful to the aquatic environment.Sudden instream releases of water from hydropower plants (hydropeaking [HP]) can cause abrupt temperature variations (thermopeaking [TP]), typically on a daily/sub-daily
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