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The loss of DDX3X attenuated the migratory capacity of PDAC cells in vitro and in vivo. DDX3X was shown to facilitate epithelial-mesenchymal transition (EMT) and the phosphorylation of p65 and eIF2α. Moreover, DDX3X displayed oncogenic activity by promoting p62 accumulation. Our results demonstrated that DDX3X activates NF-κB and promotes metastasis by inducing EMT via p62. Our results demonstrated that DDX3X activates NF-κB and promotes metastasis by inducing EMT via p62. Circular RNA (circRNA) is a special kind of noncoding RNA that play

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