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PATIENTS AND METHODS The phrase amounts of MIAT and sineoculis homeobox homolog 1 (SIX1) in OS areas and cells were recognized by quantitative real time polymerase sequence reaction and Western blot. Cell viability, apoptosis, migration and invasion of OS cells had been based on MTT, circulation cytometry and trans-well assays, respectively. The prospective connection among MIAT, miR-141-3p and SIX1 was reviewed by bioinformatics evaluation and luciferase reporter assay. Phosphatidylinositide 3-kinases (PI3K)/pr
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