https://www.selleckchem.com/pr....oducts/b102-parp-hda
We suggest that it would be relevant to study the role of PSEN within the gene regulatory network deciphered in the sea urchin.Ca2+ influx during oocyte maturation and after sperm entry is necessary to fill the internal Ca2+ stores and for complete egg activation. We knocked out the transient receptor potential vanilloid member 3 (TRPV3) and the T-type channel, CaV3.2, to determine their necessity for maintaining these functions in mammalian oocytes/eggs. Double-knockout (dKO) females were subfertile, their oocytes and eggs
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