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Although longitudinal studies have reported associations between early life factors (ie, in-utero/perinatal/infancy) and long-term suicidal behavior, they have concentrated on 1 or few selected factors, and established associations, but did not investigate if early-life factors predict suicidal behavior. To identify and evaluate the ability of early-life factors to predict suicide attempt in adolescents and young adults from the general population. This prognostic study used data from the Québec Longitudinal Study of Child Development,