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We aimed to investigate the relationship of weight change across adulthood with the risk of hearing loss. The data from National Health and Nutrition Examination Surveys. Cox proportional hazards models were applied to explore the association between weight change and risk of hearing loss. Kaplan-Meier method was used to plot the survival curves associated with weight change patterns. Compared with participants who remained at normal weight, those with stable obese participants had increased risks of total hearing loss across adulthood,